Hong Kong - Asian equity markets sank on Wednesday following a heavy selloff in New York, where a string of poor earnings reports stoked concerns about the US economy and put pressure on the dollar.
Traders are also keeping an eye on Europe as Greece's new anti-austerity government prepares to face off with its international creditors over its bailout.
Tokyo fell 0.20%, Sydney lost 0.27%, Hong Kong was 0.16% lower, Shanghai sank 1.30% and Seoul gave up 0.18%.
Global investors - already nervous owing to political uncertainty in Greece, plunging oil prices and weak world economic growth - ran for cover in US trade on Tuesday in response to negative reports from some of the world's biggest firms.
Caterpillar, Microsoft, conglomerate Procter & Gamble and mining giant Freeport-McMoRan all announced weak earnings or negative outlooks, sending their share prices plunging.
That sent Wall Street's three main indexes tumbling, with the Dow losing 1.65%, the S&P 500 off 1.34% and the Nasdaq shedding 1.89%.
READ: US stocks sink on weak earnings
Adding to the negative sentiment was news that US durable goods orders unexpectedly tumbled 3.4% in December, reminding investors that the US economy still has weak spots, especially its exposure to the global economic slowdown.
A Conference Board report showing US consumer confidence jumped in January to its highest level in more than seven years was unable to lift the mood.
After the market closed, Apple announced its quarterly profit rocketed to a corporate record of $18bn at the end of last year on booming sales of big-screen iPhone models, especially in China.
The dollar took a hit in US trade. The troubled euro - which hit a more than 11-year low below $1.10 on Monday - jumped above $1.14 at one point in New York before easing slightly to $1.1380 by the end of the day.
However, in early exchanges on Wednesday the single currency retreated to $1.1332.
The dollar was also ¥118.14 on Wednesday in Tokyo, up from ¥117.90 in New York, where at one point it sank to ¥117.40.
The euro remains in focus as Greece's new far-left Syriza leadership prepares for a standoff with the European Union and International Monetary Fund.
The party won weekend elections after campaigning to renegotiate the country's vast bailout that came with painful terms including spending cuts and high taxes.
READ: Anti-austerity economist to head Greek finance
Both sides appear ready to fight with EU officials warning Prime Minister Alexis Tsipras not to seek any debt write-off or other radical change to the rescue programme.
"If the continuation of the programme of aid for Greece is called into question... Greek banks would lose access to central bank funds," Joachim Nagel, a member of the Bundesbank's executive board, warned in a Handelsblatt interview.
On oil markets the two main contracts resumed their downtrend after jumping on Tuesday in reaction to the weaker dollar.
READ: Oil slips ahead of Fed meeting outcome
US benchmark West Texas Intermediate for March delivery slipped 82 cents to $45.41. The contract rose $1.08 on Tuesday.
Brent North Sea crude - which jumped $1.44 in the previous session - shed 75 cents to $48.85.
Gold fetched $1 291.50 an ounce, against $1 280.38 late on Tuesday.